James Conner vs Samaje Perine: The Full Breakdown
Deciding between James Conner and Samaje Perine is a common lineup dilemma for fantasy managers. The Arizona Cardinals running back put up 11.0 PPG in 2025 over 14 games; Samaje Perine of the Kansas City Chiefs averaged 6.5 in 15. A 4.5-point margin that could shift on any given week.
The per-game difference of 4.5 points favors James Conner, though savvy managers know that gap can shrink or widen depending on the weekly slate. Defensive matchup, recent scoring trends, and health status all shift the calculus from one running back to the other.
Both profile as early-down workhorses. James Conner ran for 752 yards and 5 touchdowns; Samaje Perine posted 285 and 2. Goal-line share, red zone touches, and which team is favored are usually the tiebreaker when neither back offers passing-game volume.
One scheduling note: James Conner is off Week 11 and Samaje Perine Week 6. If these two are on your roster, you will need a fill-in running back for both weeks. DraftCall flags bye conflicts so you can plan ahead rather than panic on waivers.
