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Head to Head

Updated from live stats

Brandon Aiyuk or James CookWho should you draft or start in 2026 fantasy football?

Heads up: Brandon Aiyuk is listed out as of . The call below weighs season production, not this week's status.

Brandon Aiyuk is a San Francisco 49ers wide receiver who averaged 11.8 fantasy points per game across 13 games in 2025. James Cook is a Buffalo Bills running back who averaged 16.8 fantasy points per game across 17 games in 2025. Both stat lines are below. The start or sit verdict, with this week's matchup and injury status factored in, is in the DraftCall app.

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DraftCall's AI analyzes matchup quality, recent trends, injury impact, and game script to give you a clear start/sit recommendation.

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Inside the app

  • DraftCall opening screen. Plain-English fantasy help, from your first draft to game day.
  • Compare screen. Pick any two players and DraftCall calls it in seconds, with PPR, half, standard, and TE premium scoring toggles.
  • Verdict screen. A start-or-sit call between two quarterbacks with a confidence percentage, a confidence meter, and the key factors behind the decision.
  • Verdict detail. Boom and bust projection ranges for both players, then a stat-by-stat tale of the tape covering points per game, passing touchdowns, and rushing touchdowns.
  • Quick Add screen with the microphone live. Say a player name and DraftCall fills the roster slot, with a level meter showing it listening.
  • My Team screen. Every starter with points per game, opponent, and recent form, plus a combined lineup total for the week.
  • Bye Week Planner. A season grid showing which week each player is off, with the trouble weeks where more than one starter is out called out below it.
WRSan Francisco 49ers
Brandon Aiyuk
PPG
11.8
Games
13
Rec
58
Rec Yds
762
Rec TDs
5
Targets
82
Bye
Week 9
RBBuffalo Bills#6 RB
James Cook
PPG
16.8
Games
17
Rush Yds
1,621
Rush TDs
12
Rec
33
Rec Yds
291
Bye
Week 7

Detailed Stat Breakdown

Brandon Aiyuk vs James Cook: 2025 fantasy football stats in the half-PPR scoring format.
StatBrandon AiyukJames Cook
PPG (Half-PPR)11.816.8
Games Played1317
Total Fantasy Pts (est.)153286
Rushing Yards01,621
Rush Yds/Game0.095.4
Rushing TDs012
Receptions5833
Receiving Yards762291
Targets8240
Total TDs514
Age-27
Experience-3 yrs
Bye WeekWeek 9Week 7

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Track Brandon Aiyuk and James Cook live in the DraftCall app.

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Frequently Asked Questions

Should I start Brandon Aiyuk or James Cook in fantasy football?▾

The start or sit verdict for Brandon Aiyuk and James Cook is in the DraftCall app, where it accounts for this week's matchup, recent form and injury status. On the stats alone, Brandon Aiyuk averaged 11.8 fantasy points per game in 2025 and James Cook averaged 16.8.

Should I draft Brandon Aiyuk or James Cook in 2026 fantasy football?▾

Brandon Aiyuk averaged 11.8 fantasy points per game across 13 games in 2025, and James Cook averaged 16.8 across 17. Both stat lines and bye weeks are on this page. For a pick between the two, compare them in the DraftCall app.

How many fantasy points did Brandon Aiyuk and James Cook average in 2025?▾

Brandon Aiyuk averaged 11.8 fantasy points per game (half-PPR) across 13 games in 2025. James Cook averaged 16.8 PPG over 17 games. That is a difference of 5.0 points per game.

When are Brandon Aiyuk and James Cook's bye weeks in 2026?▾

Brandon Aiyuk (SF) has a bye in Week 9, and James Cook (BUF) has a bye in Week 7. Plan your roster accordingly if you are carrying both players.

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