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Head to Head

Updated from live stats

Amon-Ra St. Brown vs Joe MixonWho should you start in 2026 fantasy football?

DraftCall Analytics

Start Joe Mixon over Amon-Ra St. Brown in 2026.

Joe Mixon averaged 16.5 PPG in 2025 to Amon-Ra St. Brown's 15.6, a 0.9 point per game edge. They play different positions, so weigh the per-game edge against what your roster needs at RB and WR.

The Bottom Line

Cross-position decisions depend on league format. In half-PPR, Joe Mixon (16.5 PPG) is the higher-floor play. Amon-Ra St. Brown (15.6 PPG) could win a specific week on touchdown variance. For FLEX spots, lean toward the player with the softer defensive matchup that week rather than defaulting to season averages.

Low confidence: the production gap is narrow enough that weekly context matters more than the season line.

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WRDetroit Lions#4
Amon-Ra St. Brown
PPG
15.6
Games
17
Rec
117
Rec Yds
1,401
Rec TDs
11
Targets
172
Bye
Week 6
RBHouston Texans#99PPG LEADER
Joe Mixon
PPG
16.5
Games
15
Rush Yds
1,165
Rush TDs
11
Rec
32
Rec Yds
240
Bye
Week 14

The Edge Chart

VolumeEfficiencyTD UpsideFloorCeilingDurability
Amon-Ra St. Brown
Joe Mixon

Head to Head

15.6 PPG16.5 PPG
17 GP15 GP
Bye: Week 6Bye: Week 14

Fantasy Tiers

Amon-Ra St. Brown: Tier 1 (Elite) WR (ranked #4 at the position). Joe Mixon: Unranked RB. Comparing across positions, raw PPG is less useful than positional scarcity. A Tier 1 (Elite) WR is harder to replace on waivers than an Unranked RB in most league formats.

Amon-Ra St. Brown vs Joe Mixon: The Full Breakdown

Comparing Amon-Ra St. Brown (WR, Detroit Lions) against Joe Mixon (RB, Houston Texans) means weighing two different roles in your fantasy lineup. Amon-Ra St. Brown averaged 15.6 PPG in 2025 over 17 games, while Joe Mixon posted 16.5 PPG across 15 games.

Cross-position FLEX decisions cannot be made on PPG alone. Positional scarcity, matchup quality, floor versus ceiling, and league scoring format all shift the answer. A 14 PPG tight end in a thin TE week is often worth more than a 16 PPG receiver in a deep WR week, because the opportunity cost on the waiver wire is wildly different.

DraftCall's AI engine weighs all of these signals and returns a verdict with clear reasoning, so you are not cross-referencing four different rankings tabs on a Sunday morning.

Amon-Ra St. Brown has his bye in Week 6, Joe Mixon in Week 14. Plan your FLEX rotation around those weeks, especially if either player is anchoring your roster.

Trade Value + Dynasty Outlook

Both are in a similar trade value range. A straight swap would be fair in most leagues, with the tiebreaker going to whichever manager values schedule or bye week more. Dynasty outlook: Amon-Ra St. Brown (age 26) is in the middle of his productive window. Stable dynasty value. Joe Mixon (age 27) is approaching the age where RB production historically drops. Sell-high window is open.

Did You Know?

  • Joe Mixon outscored Amon-Ra St. Brown by a projected 15 total fantasy points over a full 17-game season.
  • Amon-Ra St. Brown played 17 games in 2025 compared to Joe Mixon's 15. That durability gap means Amon-Ra St. Brown contributed more total fantasy points even before you look at per-game averages.
  • Joe Mixon scored 12 total touchdowns in 2025 (0.8 per game), making him one of the more reliable scoring options at running back.

Detailed Stat Breakdown

Amon-Ra St. Brown vs Joe Mixon: 2025 fantasy football stat comparison in the half-PPR scoring format.
StatAmon-Ra St. BrownJoe Mixon
PPG (Half-PPR)15.616.5
Games Played1715
Total Fantasy Pts (est.)265248
Rushing Yards91,165
Rush Yds/Game0.577.7
Rushing TDs011
Receptions11732
Receiving Yards1,401240
Targets1720
Total TDs1112
Age26-
Experience4 yrs-
Bye WeekWeek 6Week 14

Summary

The 2025 numbers favor Joe Mixon at 16.5 PPG, 0.9 points per game above Amon-Ra St. Brown's 15.6. But season stats only tell part of the story. DraftCall's AI factors in weekly matchup, recent form, and injury status to give you a verdict that updates with the latest data.

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Frequently Asked Questions

Should I start Amon-Ra St. Brown or Joe Mixon in fantasy football?

Based on 2025 season averages, Joe Mixon has the edge at 16.5 PPG compared to Amon-Ra St. Brown's 15.6 PPG. However, the best start depends on weekly matchup, recent form, and injury status. DraftCall's app provides real-time AI-powered verdicts that factor in all of these variables.

How many fantasy points did Amon-Ra St. Brown and Joe Mixon average in 2025?

Amon-Ra St. Brown averaged 15.6 fantasy points per game (half-PPR) across 17 games in 2025. Joe Mixon averaged 16.5 PPG over 15 games. That is a difference of 0.9 points per game.

When are Amon-Ra St. Brown and Joe Mixon's bye weeks in 2026?

Amon-Ra St. Brown (DET) has a bye in Week 6, and Joe Mixon (HOU) has a bye in Week 14. Plan your roster accordingly if you are carrying both players.